How Can You Remove JS:Iframe-CLO [Trj]? - Step by Step Removal Guide

"When the computer starts, a Windows Script Host dialog says 'C:\Users\<user>\miscrosofts.vbs' script can't be loaded because it is being accessed by another process. After that, every once in a while avast shows the alert 'trojan horse blocked'.
Object : some address
Infection : JS:Iframe-CLO [Trj]
Process : notorious iexplorer.exe

Miscrosofts.vbs text - http://pastebin.com/Yfk4G6hb. From what I gather the script is visiting the sites mentioned in miscrosofts.vbs through IE. I can't delete it with File Assassin. Deleted from the linux, reappeared after starting windows."

Information about JS:Iframe-CLO [Trj]

JS:Iframe-CLO [Trj] is a Trojan horse which is capable of making chaos on Windows operating system seriously. Usually, you may get infected by it via free downloads. Its other sources are spam email attachments, malicious links in social media sites and instant messaging programs. Once infected, you may sense that your PC is abnormal. It tries to get to a certain website and sends your information to it. Your anti-virus program may detect it out but fail to fully remove. You need to be cautious.